2024
Midbrain glutamatergic circuit mechanism of resilience to socially transferred allodynia in male mice
Yi Han*, Lin Ai*, Lingzhen Song*, Yu Zhou*, Dandan Chen, Sha Sha, Ran Ji, Qize Li, Qingyang Bu, Xiangyu Pan, Xiaojing Zhai, Mengqiao Cui, Jiawen Duan, Junxia Yang, Dipesh Chaudhury, Ankang Hu, He Liu, Ming-Hu Han, Jun-Li Cao, Hongxing Zhang. Nature Communications. doi.org/10.1038/s41467-024-49340-8
*equal contribution
Optic-fiber-based optogenetic stimulator with µ LED and 3D-printed structures for brain stimulation
Keonghwan Oh, Mohsin Mohammed, Revathi Sukesan, Aleksa Petkovic, Dipesh Chaudhury & Sohmyung Ha. IEEE Access (accepted)
2023
Nighttime-specific gene expression changes in suprachiasmatic nucleus and habenula are associated with resiliency to chronic social stress
Priyam Narain*, Aleksa Petkovic*, Marko Susic*, Salma Haniffa, Nizar Drou, Marc Arnoux, Mariam Anwar, Dipesh Chaudhury. Biorxiv. doi.org/10.1101/2023.09.05.556324. https://biorxiv.org/cgi/content/short/2023.09.05.556324v1
*equal contribution
Chronic social stress blunts core body temperature and molecular rhythms of Cirbp and Rbm3 in mice lateral habenula.
Salma Haniffa*, Priyam Narain*, Michelle Ann Hughes, Aleksa Petković, Marko Šušić, Vongai Mlambo & Dipesh Chaudhury (2023). Open Biology. doi.org/10.1101/2023.09.05.556324.
*equal contribution
Neural and molecular investigation into the paraventricular thalamic-nucleus accumbens circuit for pain sensation and non-opioid analgesia.
Guangchao Zhang, Mengqiao Cui, Ran Ji, Shiya Zou, Lingzhen Song, Bingqian Fan, Li Yang, Di Wang, Suwan Hu, Xiao Zhang, Tantan Fang, Xiaolu Yu, Jun-Xia Yang, Dipesh Chaudhury, He Liu, Ankang Hu, Hai-Lei Ding, Jun-Li Cao & Hongxing Zhang (2023). Pharmacological Research. 191: 106776. DOI: 10.016/j.phrs.2023.106776.
2022
Encore: Behavioural Animal Models of Stress and Mood Disorders.
Aleksa Petkovic, Dipesh Chaudhury (2022). Encore: Behavioural Animal Models of Stress and Mood Disorders. Frontiers in Behavioural Neuroscience.
2021
Sleep-Wake Dynamics Pre- and Post-Exposure to Chronic Social Stress.
Basma Radwan, Gloria Jansen, Dipesh Chaudhury (2021). iScience. 24(10):103204. doi:10.1016/j.isci.2021.103204
Blunted Diurnal Firing in Lateral Habenula Projections to Dorsal Raphe Nucleus and Delayed Photoentrainment in Stress- Susceptible Mice.
He Liu, Ashutosh Rastogi, Priyam Narain, Qing Xu, Merima Sabanovic, Ayesha Darwish Alhammadi, Lihua Guo, Jun-Li Cao, Hongxing Zhang, Hala Aqel, Vongai Mlambo, Rachid Rezgui, Basma Radwan & Dipesh Chaudhury (2021). Plos Biology. 19 (3); doi: 10.1371/journal.pbio.3000709
Prolonged Exposure to Social Stress Impairs Homeostatic Sleep Regulation
Basma Radwan, Alvaro Yanez Touzet, Soaad Hammami and Dipesh Chaudhury (2021). Frontiers in Neuroscience. 15; doi: 10.3389/fnins.2021.633955.
Abnormal Sleep Signals Vulnerability to Chronic Social Defeat Stress.
Basma Radwan, Gloria Jansen, Dipesh Chaudhury (2021). Frontiers in Neuroscience. 14; doi: 10.3389/fnins.2020.610655.
2020
What it takes to be at the top: The interrelationship between chronic social stress and social dominance.
Merima Šabanović, He Liu, Vongai Mlambo, Hala Aqel, Dipesh Chaudhury (2020). Brain and Behaviour. 10 (12); e01896.
2019
Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression. Biological Psychiatry
Ja Wook Koo, Dipesh Chaudhury, Ming-Hu Han and Eric Nestler (2019), DOI: 10.1016.
A key noradrenergic brainstem-mesolimbic circuit: promotion of resilience to social stress. Chronic Stress
Hongxing Zhang, Dipesh Chaudhury, Sarah Montgomery, Jun-Li Cao and Ming-Hu (2019). Chronic Stress (Commentary).
The role of dopamine in aversively motivated behavior.
Basma Radwan, He Liu and Dipesh Chaudhury (2019). Volume 1713 of Brain Research (BRES).
2018
The role of dopamine in mood disorders and the associated changes in circadian rhythms and sleep-wake cycle.
Basma Radwan, He Liu and Dipesh Chaudhury (2018). Brain Research, 18: 30597.
Modeling of inhomogeneous electromagnetic field in the nervous system: a novel paradigm in understanding cell interactions, disease etiology and therapy.
Isakovic J, Dobbs-Dixon I, Dipesh Chaudhury and Mitrecic D (2018). Scientific Reports, 8; 12909.
Alpha1 and beta3 adrenergic receptor-mediated mesolimbic homeostatic plasticity confers resilience to social stress in susceptible mice.
Hongxing Zhang, Dipesh Chaudhury, Alexander R. Nectow, Allyson K. Friedman, Song Zhang, Barbara Juarez, He Liu, Madeline L. Pfau, Hossein Aleyasin, Cheng Jiang, Marshall Crumiller, Erin S. Calipari, Stacy M. Ku, Carole Morel, Nikos Tzavaras, Sarah E. Montgomery, Michelle He, Stephen R. Salton, Scott J. Russo, Eric J. Nestler, Jeffrey M. Friedman, Jun-Li Cao, and Ming-Hu Han. (2018). Biological Psychiatry, 18; 31818.
2017
Midbrain circuit regulation of individual alcohol drinking behaviors in mice.
Barbara Juarez, Carole Morel, Stacy M. Ku, Yutong Liu, Hongxing Zhang, Sarah Montgomery, Hilledna Gregoire, Efrain Ribeiro, Marshall Crumiller, Ciorana Roman-Ortiz, Jessica J. Walsh, Kelcy Jackson, Denise E. Croote, Yingbo Zhu, Song Zhang, Leandro F. Vendruscolo, Scott Edwards, Amanda Roberts, Georgia E. Hodes, Yongke Lu, Erin S. Calipari, Dipesh Chaudhury, Allyson K. Friedman & Ming-Hu Han (2017). Nat. Communications, December 20; 8(1):2220 [A, E, I].
Understanding Mood Disorders Using Electrophysiology and Circuit Breaking.
He Liu and Dipesh Chaudhury. In Book: Decoding Neural Circuit Structure and Function: Cellular Dissection Using Genetic Model Organisms.Chapter 14, Page 343-370. (Book Chapter - Springer International Publication) Editors: Arzu Celik and Mathias F. Wernet, 2017. https://link.springer.com/book/10.1007/978-3-319-57363-2.
2016
Regulation and modulation of depression-related behaviours: Role of dopaminergic neurons.
Basma Radwan, He Liu and Dipesh Chaudhury. Dopamine and Sleep (Book Chapter-Springer) Editors: Jaime Monti, SR Pandi-Perumal and S. Chokroverty, 2016.
Basal forebrain projections to the lateral habenula modulate aggression reward
Sam A. Golden, Mitra Heshmati1, Meghan Flanigan, Dan J. Christoffel, Kevin Guise, Madeline L. Pfau, Hossein Aleyasin, Caroline Menard, Hongxing Zhang, Georgia E. Hodes, Dana Bregman, Lena Khibnik, Jonathan Tai, Nicole Rebusi, Brian Krawitz, Dipesh Chaudhury, Jessica J. Walsh, Ming-Hu Han, Matt L. Shapiro & Scott J. Russo. Nature, 2016.
KCNQ channel openers reverse depressive symptoms via an active resilience mechanism
Allyson Friedman, Barbara Juarez, Stacy Ku, Hongxing Zhang, Jessica Walsh, Dipesh Chaudhury, Angel Hawkins, Song Zhang, Rhodora Calizo, David Dietz, James Murrough, Maria Ribadeneira, Erik Wong, Rachael Neve and Ming-Hu Han. Nat. Communication, 2016.
2015
Neuronal Correlates of Depression
Dipesh Chaudhury, He Liu, Ming-Hu Han. Cellular and Molecular Life Science. 72: 4681-4920. 2015.
Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression
Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, Chaudhury D, Persaud B, Cachope R, Bolaños-Guzmán CA, Cheer J, Deisseroth K, Han MH, Nestler EJ. Nat Commun. 8: 8062. 2015.
2014
Optogenetics: Illuminating the neural basis of rodent behavior
Francis TC, Chaudhury D, Lobo MK. Open Access Animal Physiology. 6:33-51. (2014).
Loss of BDNF Signaling in D1R-Expressing NAc Neurons Enhances Morphine Reward by Reducing GABA Inhibition
Koo JW, Lobo MK, Chaudhury D, Labonté B, Friedman A, Heller E, Peña CJ, Han MH, Nestler EJ. Neuropsychopharmacology. 2014 Oct;39(11):2646-53.
Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience
Friedman AK, Walsh JJ, Juarez B, Ku SM, Chaudhury D, Wang J, Li X, Dietz DM, Pan N, Vialou VF, Neve RL, Yue Z, Han MH. Science, 2014 Apr 18;344(6181):313-9.
Cocaine-mediated reduction of G9a activity promotes a striatopallidal to striatonigral ‘switching’ phenotype and enhanced drug sensitivity
Ian Maze, Dipesh Chaudhury, David M. Dietz, Melanie Von Schimmelmann, Mary K. Lobo, Rosemary C. Bagot, Pamela J. Kennedy, HaoSheng Sun, Gustavo Turecki, Alexander Tarakhovsky, Paul Greengard, Ming-Hu Han, Anne Schaefer and Eric J. Nestler . Nature Neuroscience 2014.
2013
Stress gates neural activation of BDNF in the mesolimbic reward pathway.
Jessica J. Walsh, Allyson K. Friedman, Haosheng Sun, Elizabeth A. Heller, Stacy M. Ku, Barbara Juarez, Veronica L. Burnham, Michelle S. Mazei-Robison, Deveroux Ferguson, Sam A. Golden, Ja Wook Koo, Dipesh Chaudhury, Daniel J. Christoffel, Lisa Pomeranz, Jeffrey M. Friedman, Scott J. Russo, Eric J. Nestler & Ming-Hu Han. Nature Neuroscience, 2013.
Delta-FosB Induction in Striatal Medium Spiny Neuron Subtypes in Response to Chronic Pharmacological, Emotional, and Optogenetic Stimuli.
Mary Kay Lobo, Samir Zaman, Diane Damez Werno, Ja Wook Koo, Rosemary Bagot, Jennifer DiNieri, Alexandria Nugent, Eric Finkel, Dipesh Chaudhury, Ramesh Chandra, Efrain Riberio, Jacqui Rabkin, Ezekiell Mouzon, Roger Cachope, Joseph Cheer, Ming-Hu Han, David Dietz, David Self, Yasmin Hurd, Vincent Vialou, and Eric Nestler. The Journal of Neuroscience, 2013.
Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine cytoskeleton regulator Tiam1
Ramesh Chandra, Jeffrey Lenz, Amy M. Gancarz, Dipesh Chaudhury, Gabrielle L. Schroeder, Ming-Hu Han, Joseph F. Cheer, David M. Dietz, Mary Kay Lobo. Frontiers In Neuroscience, 2013.
Class i hdac inhibition blocks cocaine-induced plasticity through targeted changes in histone methylation
Pamela J. Kennedy, Jian Feng, A.J. Robison, Ian Maze, Ana Badimon, Ezekiell Mouzon, Dipesh Chaudhury, Diane M. Damez-Werno, Stephen J. Haggarty, Ming-Hu Han, Rhonda Bassel-Duby, Eric N. Olson & Eric J. Nestler. Nature Neuroscience, 2013; doi:10.1038/nn.3354.
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons
Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, Lobo MK, Neve RL, Friedman JM, Russo SJ, Deisseroth K, Nestler EJ, Han MH. Nature, 2013 Jan 24; 493(7433):532-6.
2012
BDNF is a negative modulator of morphine action
Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Dietz DM, Lobo MK, Neve RL, Russo SJ, Han MH, Nestler EJ. Science, 2012 Oct 5; 338(6103):124-8.
2011
Odor fear conditioning modifies piriform cortex local field potentials both during conditioning and during post-conditioning sleep
Barnes DC, Chapuis J, Chaudhury D, Wilson DA. PLoS One, 2011 Mar 23; 6(3):e18130.
2010
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward
Lobo MK, Covington HE 3rd, Chaudhury D, Friedman AK, Sun H, Damez-Werno D, Dietz DM, Zaman S, Koo JW, Kennedy PJ, Mouzon E, Mogri M, Neve RL, Deisseroth K, Han MH, Nestler EJ. Science, 2010 Oct 15; 330(6002):385-90.
Olfactory bulb habituation to odor stimuli
Dipesh Chaudhury, Laura Manella, Adolfo Arellanos, Olga Escanilla, Thomas A. Cleland and Christiane Linster. Behavioral Neuroscience, 2010; 124 (4) 490-499.
2009
Bulbar acetylcholine enhances neural and perceptual odor discrimination
Dipesh Chaudhury, Olga Escanilla, and Christiane Linster. The Journal of Neuroscience, January 7, 2009; 29(1):52– 60.
2008
Select cognitive deficits in vasoactive intestinal peptide deficient mice
Dipesh Chaudhury, Dawn H Loh, Joanna M Dragich, Arkady Hagopian and Christopher S Colwell. BMC Neuroscience, 2008; 9:63.
2005
Melatonin inhibits hippocampal long term potentiation
Louisa M. Wang, Nanthia A. Suthana, Dipesh Chaudhury, David R. Weaver, and Christopher S. Colwell. European Journal of Neuroscience, 2005; 22, 2231-2237.
Circadian regulation of hippocampal long-term potentiation
Chaudhury, D., Wang, LW and Colwell, CS. Journal of Biological Rhythms, 2005; 20, 225-236.
2002
Circadian modulation of learning and memory in fear-conditioned mice
Chaudhury, D., and Colwell, CS. Behavioural Brain Research, 2002; 133, 95-108.
1999
Passive avoidance training results in increased responsiveness of voltage and ligand-gated channels in chick synaptoneurosomes
Salinska, E.J., Chaudhury, D., Bourne, R.C. and Rose, S.P.R. Neuroscience, 1999; 93(4):1507-14.
